SCHEMBL8701548

SCHEMBL8701548

O=C(CCN1CCCCC1CO)Nc1ccc2c(c1)C(=O)c1ccc(NC(=O)CCN3CCCCC3CO)cc1C2=O

nearest known ligand 0.98

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TERT O14746 20/20 0.98
ALDH1A1 P00352 1/20 0.64
MAPT P10636 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8705974 0.91 TERT (0.98) TERTALDH1A1MAPT
SCHEMBL5338203 0.81 TERT (0.93) TERT
SCHEMBL4298492 0.80 TERT (1.00) TERTALDH1A1MAPT
SCHEMBL8704683 0.80 TERT (1.00) TERTALDH1A1MAPT
SCHEMBL8703020 0.79 TERT (0.64) TERT
SCHEMBL8706042 0.78 TERT (1.00) TERTALDH1A1MAPT
SCHEMBL8706439 0.78 TERT (1.00) TERTALDH1A1MAPT
SCHEMBL3115635 0.78 TERT (1.00) TERTALDH1A1MAPT
SCHEMBL4300594 0.78 TERT (1.00) TERTALDH1A1MAPT
SCHEMBL9629969 0.75 TERT (1.00) TERTALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0482119-A1 INTERCALATING AGENTS CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) 1992-04-29 EP claimed
WO-1991000265-A1 INTERCALATING AGENTS CANCER RESEARCH TECHNOLOGY LTD. (GB) 1991-01-10 WO claimed
WO-1998025885-A1 ANTHRAQUINONES WITH BIOLOGICAL ACTIVITY CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) 1998-06-18 WO disclosed
EP-0482119-A1 INTERCALATING AGENTS CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) 1992-04-29 EP disclosed
WO-1991000265-A1 INTERCALATING AGENTS CANCER RESEARCH TECHNOLOGY LTD. (GB) 1991-01-10 WO disclosed