SCHEMBL5338203

SCHEMBL5338203

O=C(CCN1CCCCC1CO)Nc1ccc2[nH]c3ccc(NC(=O)CCN4CCCCC4CO)cc3c(=O)c2c1

nearest known ligand 0.93

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TERT O14746 19/20 0.93
P2RY12 Q9H244 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5335530 0.87 TERT (1.00) TERTP2RY12
SCHEMBL5332779 0.83 TERT (1.00) TERT
SCHEMBL5337897 0.81 TERT (1.00) TERTP2RY12
SCHEMBL8701548 0.81 TERT (0.98) TERT
SCHEMBL5339895 0.80 TERT (1.00) TERTP2RY12
SCHEMBL5332038 0.78 TERT (1.00) TERT
SCHEMBL5336373 0.78 TERT (1.00) TERTP2RY12
SCHEMBL5341217 0.78 TERT (0.98) TERTP2RY12
SCHEMBL14355586 0.75 TERT (1.00) TERTP2RY12
SCHEMBL8705974 0.73 TERT (0.98) TERT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7300930-B2 Therapeutic acridone and acridine compounds CANCER RESEARCH TECHNOLOGY LIMITED (GB) 2007-11-27 US disclosed
US-7300930-B2 Therapeutic acridone and acridine compounds CANCER RESEARCH TECHNOLOGY LIMITED (GB) 2007-11-27 US disclosed
US-7300930-B2 Therapeutic acridone and acridine compounds CANCER RESEARCH TECHNOLOGY LIMITED (GB) 2007-11-27 US disclosed
US-7160896-B2 Therapeutic acridone and acridine compounds CANCER RESEARCH TECHNOLOGY LIMITED (GB) 2007-01-09 US disclosed
US-7160896-B2 Therapeutic acridone and acridine compounds CANCER RESEARCH TECHNOLOGY LIMITED (GB) 2007-01-09 US disclosed
US-7160896-B2 Therapeutic acridone and acridine compounds CANCER RESEARCH TECHNOLOGY LIMITED (GB) 2007-01-09 US disclosed
US-20060111389-A1 Therapeutic acridone and acridine compounds CANCER RESEARCH TECHNOLOGY LIMITED (GB) 2006-05-25 US disclosed
EP-1363888-A2 THERAPEUTIC ACRIDONE AND ACRIDINE COMPOUNDS Cancer Research Technology Limited (GB) 2003-11-26 EP disclosed
WO-2002008193-A2 THERAPEUTIC ACRIDONE AND ACRIDINE COMPOUNDS CANCER RESEARCH TECHNOLOGY LIMITED (GB) 2002-01-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060111389-A1 Therapeutic acridone and acridine compounds TERT, ACIN1, NAT1 TERT 1/4885P2RY12 3821/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.