Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.60 |
| ▸ | MAPT | P10636 | 5/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | POLB | P06746 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | NR4A1 | P22736 | 2/20 | 0.59 |
| ▸ | MYC | P01106 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8706283 | 0.84 | KDM4E (0.45) | KDM4EMAPTALDH1A1POLBMEN1 | |
| SCHEMBL8703968 | 0.83 | AOC2 (0.42) | KDM4EMAPTALDH1A1POLBMEN1 | |
| SCHEMBL17172446 | 0.82 | KDM4E (0.67) | KDM4EMAPTALDH1A1POLBMEN1 | |
| Hydrochloric Acid SCHEMBL8703585 | 0.82 | AOC2 (0.41) | KDM4EMAPTALDH1A1POLBMEN1 | |
| SCHEMBL16720590 | 0.81 | KDM4E (0.74) | KDM4EMAPTALDH1A1POLBMEN1 | |
| Hydrochloric Acid SCHEMBL8705820 | 0.81 | AOC2 (0.42) | KDM4EMAPTALDH1A1POLBMEN1 | |
| SCHEMBL8705516 | 0.79 | AOC2 (0.68) | MAPTALDH1A1MEN1KMT2ATDP1 | |
| Hydrochloric Acid SCHEMBL8700020 | 0.78 | AOC2 (0.66) | MAPTALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL8705529 | 0.77 | AOC2 (0.59) | ALDH1A1POLBMEN1KMT2ATDP1 | |
| SCHEMBL8699862 | 0.76 | AOC2 (0.42) | KDM4EMAPTPOLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5824691-A | CARDIOVASCULAR, CEREBROVASCULAR, RENAL DISEASES; SHOCK, ARTERIOSCLEROSIS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-10-20 | — | — | US | disclosed |