Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC2 | O75106 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 3/20 | 0.39 |
| ▸ | F10 | P00742 | 3/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.39 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.39 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | PLK4 | O00444 | 1/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | CHUK | O15111 | 1/20 | 0.38 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | PAK4 | O96013 | 1/20 | 0.38 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.38 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8701063 | 0.99 | AOC2 (0.41) | AOC2F2F10PRSS1PRSS2 | |
| SCHEMBL8700313 | 0.90 | AOC2 (0.43) | AOC2F2F10PRSS1PRSS2 | |
| Hydrochloric Acid SCHEMBL8699397 | 0.88 | AOC2 (0.43) | AOC2F2F10PRSS1PRSS2 | |
| Hydrochloric Acid SCHEMBL8705820 | 0.85 | AOC2 (0.42) | AOC2F2F10PRSS1PRSS2 | |
| SCHEMBL8700691 | 0.80 | AOC2 (0.40) | AOC2F2F10PRSS1PRSS2 | |
| SCHEMBL8699348 | 0.80 | AOC2 (0.40) | AOC2F2F10PRSS1PRSS2 | |
| Hydrochloric Acid SCHEMBL8700230 | 0.79 | AOC2 (0.39) | AOC2F2F10PRSS1PRSS2 | |
| Hydrochloric Acid SCHEMBL8700025 | 0.79 | AOC2 (0.40) | AOC2F2F10PRSS1PRSS2 | |
| SCHEMBL8700634 | 0.79 | F10 (0.45) | AOC2F2F10PRSS1PRSS2 | |
| SCHEMBL8705516 | 0.78 | AOC2 (0.68) | AOC2TDP1CTDSP1L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5824691-A | CARDIOVASCULAR, CEREBROVASCULAR, RENAL DISEASES; SHOCK, ARTERIOSCLEROSIS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-10-20 | — | — | US | disclosed |