SCHEMBL8701577

SCHEMBL8701577

CC(=CCC(O)COCCC#N)C(=O)O

nearest known ligand 0.31

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CHRNA7 P36544 1/20 0.31
KDM4E B2RXH2 1/20 0.31
USP2 O75604 1/20 0.31
ALDH1A1 P00352 1/20 0.31
ALOX15 P16050 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3619332 0.86 ALDH1A1 (0.35) KDM4EUSP2ALDH1A1ALOX15
SCHEMBL3619334 0.86 ALDH1A1 (0.35) KDM4EUSP2ALDH1A1ALOX15
SCHEMBL1260034 0.79 USP2 (0.49) KDM4EUSP2ALDH1A1ALOX15
SCHEMBL8638825 0.79 USP2 (0.49) KDM4EUSP2ALDH1A1ALOX15
SCHEMBL6250559 0.78 TSHR (0.36) KDM4EUSP2ALDH1A1ALOX15
SCHEMBL6250554 0.78 TSHR (0.36) KDM4EUSP2ALDH1A1ALOX15
SCHEMBL2763358 0.77 MAPT (0.33) KDM4EUSP2ALDH1A1ALOX15
SCHEMBL5050873 0.77 MAPT (0.33) KDM4EUSP2ALDH1A1ALOX15
SCHEMBL4291479 0.77 USP2 (0.53) KDM4EUSP2ALDH1A1ALOX15
SCHEMBL14717768 0.77 USP2 (0.53) KDM4EUSP2ALDH1A1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0314507-B1 Pastes for forming a luminescent layer or insulator layer of a dispersion type electroluminescence element and a dispersion type electroluminescence element NIPPON KASEI CHEM (JP) 1998-01-21 EP disclosed