Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL852232 | 0.80 | HDAC3 (0.37) | ALDH1A1LMNAJAK2RAB9ASMN1; SMN2 | |
| SCHEMBL10794716 | 0.78 | ALDH1A1 (0.33) | ALDH1A1LMNAJAK2RAB9ASMN1; SMN2 | |
| SCHEMBL14920529 | 0.77 | MME (0.33) | LMNACYP2C19 | |
| SCHEMBL19666657 | 0.77 | ALDH1A1 (0.35) | ALDH1A1LMNAJAK2RAB9ASMN1; SMN2 | |
| SCHEMBL10796750 | 0.76 | ALDH1A1 (0.34) | ALDH1A1LMNAJAK2RAB9ASMN1; SMN2 | |
| SCHEMBL12783465 | 0.75 | ALDH1A1 (0.34) | ALDH1A1LMNAJAK2RAB9ASMN1; SMN2 | |
| SCHEMBL880578 | 0.75 | ALDH1A1 (0.34) | ALDH1A1LMNAJAK2RAB9ASMN1; SMN2 | |
| SCHEMBL10715777 | 0.74 | TSHR (0.36) | ALDH1A1LMNAJAK2RAB9ACYP2C19 | |
| SCHEMBL11255307 | 0.74 | NPC1 (0.51) | ALDH1A1RAB9A | |
| SCHEMBL11250957 | 0.74 | NPC1 (0.51) | ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0598753-B1 | MANGANESE COMPLEXES OF NITROGEN-CONTAINING MACROCYCLIC LIGANDS EFFECTIVE AS CATALYSTS FOR DISMUTATING SUPEROXIDE | MONSANTO CO (US) | 1998-03-18 | — | — | EP | disclosed |