Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.51 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11250957 | 1.00 | NPC1 (0.51) | NPC1RAB9APAX8CTDSP1ALDH1A1 | |
| SCHEMBL11253656 | 0.98 | NPC1 (0.49) | NPC1RAB9APAX8CTDSP1ALDH1A1 | |
| SCHEMBL11253284 | 0.81 | NPC1 (0.45) | NPC1RAB9APAX8CTDSP1ALDH1A1 | |
| SCHEMBL11259657 | 0.80 | LMNA (0.42) | NPC1RAB9APAX8ALDH1A1TDP1 | |
| SCHEMBL27991912 | 0.79 | KDM4E (0.45) | NPC1RAB9APAX8CTDSP1ALDH1A1 | |
| SCHEMBL11252169 | 0.77 | NPC1 (0.35) | NPC1RAB9APAX8ALDH1A1TDP1 | |
| SCHEMBL11247776 | 0.77 | CTSL (0.35) | NPC1RAB9APAX8ALDH1A1TDP1 | |
| SCHEMBL4044913 | 0.76 | EPHX1 (0.46) | NPC1RAB9APAX8CTDSP1ALDH1A1 | |
| SCHEMBL10808345 | 0.75 | KDM4E (0.43) | NPC1RAB9APAX8CTDSP1TDP1 | |
| SCHEMBL10810638 | 0.75 | KDM4E (0.43) | NPC1RAB9APAX8CTDSP1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4335053-A | HERBICIDES | STAUFFER CHEMICAL COMPANY (US) | 1982-06-15 | — | — | US | disclosed |
| US-4288384-A | N-Cyanoalkyl haloacetamides herbicidal antidotes | STAUFFER CHEMICAL COMPANY (US) | 1981-09-08 | — | — | US | disclosed |