Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | NT5E | P21589 | 1/20 | 0.47 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.46 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.46 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.46 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.46 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 9/20 | 0.45 |
| ▸ | CDC25B | P30305 | 8/20 | 0.45 |
| ▸ | PTPN2 | P17706 | 5/20 | 0.45 |
| ▸ | PTPN11 | Q06124 | 5/20 | 0.45 |
| ▸ | PTPN6 | P29350 | 4/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | TACR2 | P21452 | 2/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4951310 | 1.00 | HTR1A (0.47) | HTR1ANT5ESSTR1SSTR2SSTR4 | |
| SCHEMBL13498630 | 0.83 | TACR2 (0.43) | NT5ESSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL990411 | 0.82 | SSTR1 (0.59) | HTR1ANT5ESSTR1SSTR2SSTR4 | |
| SCHEMBL977853 | 0.82 | SSTR1 (0.59) | HTR1ANT5ESSTR1SSTR2SSTR4 | |
| SCHEMBL6544934 | 0.82 | SSTR1 (0.59) | HTR1ANT5ESSTR1SSTR2SSTR4 | |
| SCHEMBL6809789 | 0.82 | SSTR1 (0.59) | HTR1ANT5ESSTR1SSTR2SSTR4 | |
| SCHEMBL15973204 | 0.80 | HTR1A (0.53) | HTR1ANT5ESSTR1SSTR2SSTR4 | |
| Phosphine SCHEMBL7254654 | 0.79 | HTR1A (0.52) | HTR1ANT5ESSTR1SSTR2SSTR4 | |
| SCHEMBL21657199 | 0.79 | HTR1A (0.52) | HTR1ANT5ESSTR1SSTR2SSTR4 | |
| SCHEMBL21657117 | 0.79 | HTR1A (0.52) | HTR1ANT5ESSTR1SSTR2SSTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5795870-A | STEROID RING WITH AMINE GROUP SIDE CHAINS | TRUSTEES OF PRINCETON UNIVERSITY (US) | 1998-08-18 | — | — | US | disclosed |