Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8703561 | 1.00 | GPR88 (0.47) | GPR88FAAHTRPV1MEN1KMT2A | |
| SCHEMBL8697428 | 1.00 | GPR88 (0.47) | GPR88FAAHTRPV1MEN1KMT2A | |
| SCHEMBL8698327 | 0.99 | GPR88 (0.48) | GPR88FAAHTRPV1MEN1KMT2A | |
| SCHEMBL7964442 | 0.90 | GPR88 (0.44) | GPR88FAAHTRPV1MEN1KMT2A | |
| SCHEMBL7964655 | 0.90 | GPR88 (0.44) | GPR88FAAHTRPV1MEN1KMT2A | |
| SCHEMBL7949726 | 0.90 | GPR88 (0.44) | GPR88FAAHTRPV1MEN1KMT2A | |
| SCHEMBL7960740 | 0.88 | GPR88 (0.45) | GPR88FAAHTRPV1MEN1KMT2A | |
| SCHEMBL7961955 | 0.86 | GPR88 (0.44) | GPR88MEN1KMT2AGAA | |
| SCHEMBL7960746 | 0.86 | GPR88 (0.44) | GPR88MEN1KMT2AGAA | |
| SCHEMBL6475256 | 0.86 | FAAH (0.45) | FAAHTRPV1MEN1KMT2ACTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5830826-A | Alkoxy-alkyl-substituted 1H-3-aryl-pyrrolidine-2, 4-diones used as herbicicides and pesticides | BAYER AKTIENGESELLSCHAFT (DE) | 1998-11-03 | — | — | US | disclosed |