Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 2/20 | 0.36 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.34 |
| ▸ | TSPO | P30536 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL244403 | 0.89 | AGTR1 (0.39) | AGTR1AGTR2 | |
| SCHEMBL7471672 | 0.81 | AGTR1 (0.37) | AGTR1AGTR2TSPO | |
| SCHEMBL7422797 | 0.77 | AGTR1 (0.41) | AGTR1AGTR2 | |
| SCHEMBL244989 | 0.76 | — | — | |
| SCHEMBL8707753 | 0.75 | AGTR1 (0.37) | AGTR1AGTR2TSPOKDM4EALDH1A1 | |
| SCHEMBL8700740 | 0.74 | AGTR1 (0.37) | AGTR1AGTR2TSPOKDM4EALDH1A1 | |
| SCHEMBL7422539 | 0.73 | AGTR1 (0.31) | AGTR1AGTR2ALDH1A1 | |
| SCHEMBL7413327 | 0.73 | AGTR1 (0.39) | AGTR1AGTR2 | |
| SCHEMBL8700948 | 0.72 | — | — | |
| SCHEMBL245008 | 0.71 | AGTR1 (0.38) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5789415-A | Azacyclic-heterocyclic compounds as angiotension II receptor antagonists | PFIZER INC. (US) | 1998-08-04 | — | — | US | disclosed |