⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL244403 | 0.85 | AGTR1 (0.39) | — | |
| SCHEMBL242973 | 0.84 | — | — | |
| SCHEMBL244990 | 0.82 | GPR4 (0.42) | — | |
| SCHEMBL7416584 | 0.79 | — | — | |
| SCHEMBL243974 | 0.79 | — | — | |
| SCHEMBL21124837 | 0.76 | GPR4 (0.46) | — | |
| SCHEMBL8701715 | 0.76 | AGTR1 (0.36) | — | |
| SCHEMBL21125179 | 0.76 | — | — | |
| SCHEMBL243571 | 0.74 | — | — | |
| SCHEMBL8700948 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995002596-A1 | AZACYCLIC-HETEROCYCLIC COMPOUNDS AS ANGIOTENSIN II RECEPTOR ANTAGONISTS | PFIZER INC. (US) | 1995-01-26 | — | — | WO | claimed |
| US-20160052925-A1 | METHOD OF TREATMENT OR PROPHYLAXIS INFTAMMATORY PAIN | NOVARTIS AG (CH) | 2016-02-25 | — | — | US | disclosed |
| US-9227968-B2 | Method of treatment or prophylaxis of inflammatory pain | NOVARTIS AG (CH) | 2016-01-05 | — | — | US | disclosed |
| US-9018207-B2 | Method of treatment or prophylaxis | SPINIFEX PHARMACEUTICALS PTY LTD (AU) | 2015-04-28 | — | — | US | disclosed |
| US-20140228362-A1 | Method of Treatment or Prophylaxis | SPINIFEX PHARMACEUTICALS PTY LTD (AU) | 2014-08-14 | — | — | US | disclosed |
| US-20140142116-A1 | Method of Treatment or Prophylaxis of Inflammatory Pain | SPINIFEX PHARMACEUTICALS PTY LTD (AU) | 2014-05-22 | — | — | US | disclosed |
| US-8722675-B2 | Method of treatment or prophylaxis | SPINIFEX PHARMACEUTICALS PTY LTD (AU) | 2014-05-13 | — | — | US | disclosed |
| US-20130296350-A1 | Method of Treatment or Prophylaxis | NOVARTIS AG (CH) | 2013-11-07 | — | — | US | disclosed |
| US-8551950-B2 | Method of treatment or prophylaxis of inflammatory pain | SPINIFEX PHARMACEUTICALS PTY LTD (AU) | 2013-10-08 | — | — | US | disclosed |
| US-8492382-B2 | Method of treatment or prophylaxis | SPINIFEX PHARMACEUTICALS PTY LTD (AU) | 2013-07-23 | — | — | US | disclosed |
| US-7828840-B2 | Medical devices and methods for local delivery of angiotensin II type 2 receptor antagonists | MED INSTITUTE, INC. (US) | 2010-11-09 | — | — | US | disclosed |
| US-7795275-B2 | Method of treatment or prophylaxis | UNIQUEST PTY LIMITED (AU) | 2010-09-14 | — | — | US | disclosed |
| US-20090177267-A1 | Medical devices and methods for local delivery of angiotensin II type 2 receptor antagonists | WILMINGTON TRUST, NATIONAL ASSOCIATION, AS COLLATERAL AGENT | 2009-07-09 | — | — | US | disclosed |
| EP-1996183-A1 | METHOD OF TREATMENT OR PROPHYLAXIS INFLAMMATORY PAIN | THE UNIVERSITY OF QUEENSLAND (AU) | 2008-12-03 | — | — | EP | disclosed |
| WO-2007106938-A1 | METHOD OF TREATMENT OR PROPHYLAXIS INFLAMMATORY PAIN | THE UNIVERSITY OF QUEENSLAND (AU) | 2007-09-27 | — | — | WO | disclosed |
| EP-1830869-A1 | METHOD OF TREATMENT OR PROPHYLAXIS | THE UNIVERSITY OF QUEENSLAND (AU) | 2007-09-12 | — | — | EP | disclosed |
| US-20060223741-A1 | Method of treatment or prophylaxis | THE UNIVERSITY OF QUEENSLAND (AU) | 2006-10-05 | — | — | US | disclosed |
| WO-2006066361-A1 | METHOD OF TREATMENT OR PROPHYLAXIS | THE UNIVERSITY OF QUEENSLAND (AU) | 2006-06-29 | — | — | WO | disclosed |
| US-5789415-A | Azacyclic-heterocyclic compounds as angiotension II receptor antagonists | PFIZER INC. (US) | 1998-08-04 | — | — | US | disclosed |
| WO-1995002596-A1 | AZACYCLIC-HETEROCYCLIC COMPOUNDS AS ANGIOTENSIN II RECEPTOR ANTAGONISTS | PFIZER INC. (US) | 1995-01-26 | — | — | WO | disclosed |