Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | OXTR | P30559 | 2/20 | 0.41 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.41 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.40 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.40 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6165708 | 0.81 | ESR2 (0.56) | GPR119ESR2CA12CA1CA2 | |
| SCHEMBL6164774 | 0.78 | TTK (0.55) | GPR119ESR2PTPN1PTPN5S1PR1 | |
| Hydrogen Sulfide SCHEMBL27727970 | 0.78 | CA12 (0.53) | CA12CA1CA2CA9CA14 | |
| SCHEMBL8701834 | 0.76 | PAX8 (0.50) | GPR119ESR2PTPN1PTPN5FFAR1 | |
| SCHEMBL6414144 | 0.76 | ESR2 (0.61) | GPR119ESR2PTPN5FFAR1AKR1B1 | |
| SCHEMBL9173605 | 0.76 | CA12 (0.45) | GPR119CA12CA1CA2CA9 | |
| SCHEMBL7545306 | 0.75 | PTPN1 (0.53) | GPR119ESR2PTPN1PTPN5FFAR1 | |
| SCHEMBL2039846 | 0.75 | ESR2 (0.62) | ESR2PTPN5FFAR1AKR1B1GRIA2 | |
| SCHEMBL6959964 | 0.74 | PTPN1 (0.57) | GPR119ESR2PTPN1PTPN5FFAR1 | |
| SCHEMBL6355405 | 0.74 | CA12 (0.63) | CA12CA1CA2CA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726319-A | Biphenyl substituted dipeptide analogs promote release of growth hormone | MERCK & CO., INC. (US) | 1998-03-10 | — | — | US | disclosed |