Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 2/20 | 0.37 |
| ▸ | F10 | P00742 | 4/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | PRKG1 | Q13976 | 1/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8634120 | 0.85 | SPHK1 (0.45) | FAAHHRH3F10ITGB3ITGA2B | |
| SCHEMBL7405505 | 0.77 | HRH3 (0.43) | FAAHHRH3F10ITGB3ITGA2B | |
| SCHEMBL8686293 | 0.76 | HRH3 (0.51) | HRH3F10 | |
| SCHEMBL8681328 | 0.73 | ROCK2 (0.39) | FAAHHRH3F10ITGB3ITGA2B | |
| SCHEMBL8635435 | 0.73 | SPHK1 (0.42) | HRH3F10ITGB3ITGA2BAOC3 | |
| SCHEMBL8633220 | 0.73 | HRH3 (0.42) | FAAHHRH3F10ITGB3ITGA2B | |
| SCHEMBL27444528 | 0.72 | FAAH (0.46) | FAAHHRH3F10ITGB3ITGA2B | |
| SCHEMBL8636354 | 0.71 | FAAH (0.46) | FAAHHRH3F10ITGB3ITGA2B | |
| SCHEMBL27444529 | 0.70 | HRH3 (0.42) | FAAHHRH3F10ITGB3ITGA2B | |
| SCHEMBL1456142 | 0.68 | CKS1B (0.54) | GPR119NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750754-A | TERTIARY BUTYL 3-METHYL-4-SUBSTITUTED BUTYRATE; CHEMICAL INTERMEDIATES FOR ANTICAOGULANT DRUGS | ZENECA LIMITED (GB) | 1998-05-12 | — | — | US | disclosed |