SCHEMBL870187

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL870188	1.00	PDE4B (0.41)	PDE4BNPC1RAB9AATMPDE1B
	SCHEMBL16104302	0.92	LRRK2 (0.39)	NPSR1ALDH1A1POLBPDGFRAIDO1
	SCHEMBL3018346	0.89	PDE4B (0.49)	PDE4BKCNH2
	SCHEMBL3018341	0.89	PDE4B (0.49)	PDE4BKCNH2
	SCHEMBL870965	0.89	METAP2 (0.37)	PDE4BNPSR1TSHRCRHBPCRHR2
	SCHEMBL8181685	0.89	METAP2 (0.37)	PDE4BNPSR1TSHRCRHBPCRHR2
	SCHEMBL870966	0.89	METAP2 (0.37)	PDE4BNPSR1TSHRCRHBPCRHR2
	SCHEMBL871025	0.88	CHKA (0.41)	PDE1BTNKSFLT3
	SCHEMBL872430	0.88	CHKA (0.41)	PDE1BTNKSFLT3
	SCHEMBL872016	0.88	PDE4B (0.47)	PDE4BJAK2POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.