SCHEMBL8702012 — predicted protein targets

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	SLC22A12	Q96S37	1/20	0.33

▸	MCL1	Q07820	9/20	0.33

▸	TP53	P04637	2/20	0.32

▸	TSHR	P16473	1/20	0.32

▸	MAPT	P10636	1/20	0.32

▸	PGR	P06401	2/20	0.32

▸	BRAF	P15056	2/20	0.31

▸	JAK2	O60674	1/20	0.30

▸	BRD4	O60885	1/20	0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL8464833	0.89	MCL1 (0.35)	MCL1TP53TSHRMAPTPGR
SCHEMBL8466103	0.84	MCL1 (0.36)	MCL1TP53TSHRMAPT
SCHEMBL8464575	0.82	MCL1 (0.35)	MCL1TP53TSHRMAPT
SCHEMBL8190792	0.80	AR (0.39)	SLC22A12PGRBRD4
SCHEMBL8700190	0.78	SLC22A12 (0.33)	SLC22A12MCL1
SCHEMBL8700195	0.78	SLC22A12 (0.33)	SLC22A12MCL1
SCHEMBL8461149	0.78	AR (0.33)	MCL1BRAFBRD4
SCHEMBL1574267	0.77	AR (0.38)	SLC22A12
SCHEMBL8465633	0.76	AR (0.37)	SLC22A12PGRJAK2BRD4
SCHEMBL3555928	0.74	TSHR (0.34)	TP53TSHRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-1998028280-A1	CERTAIN 3-[2,4-DISUBSTITUTED-5-(SUBSTITUTED AMINO)PHENYL]-1-SUBSTITUTED-6-TRIFLUOROMETHYL-2,4-(1H,3H)-PYRIMIDINEDIONE DERIVATIVES AS HERBICIDES	FMC CORPORATION (US)	1998-07-02	—	—	WO	disclosed