Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 9/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 2/20 | 0.33 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.33 |
| ▸ | BRAF | P15056 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8466103 | 0.89 | MCL1 (0.36) | MCL1TP53TSHRBRPF1MAPT | |
| SCHEMBL8702012 | 0.89 | SLC22A12 (0.33) | MCL1BRD4TP53TSHRBRAF | |
| SCHEMBL8461149 | 0.88 | AR (0.33) | MCL1BRD4ARBRAF | |
| SCHEMBL8464575 | 0.86 | MCL1 (0.35) | MCL1TP53TSHRBRPF1MAPT | |
| SCHEMBL8190792 | 0.84 | AR (0.39) | BRD4ARPGR | |
| SCHEMBL9679435 | 0.83 | PPOX (0.35) | TP53BRPF1PGRMAPT | |
| SCHEMBL7833797 | 0.82 | PSIP1 (0.33) | BRD4BRPF1BRAFPGRMAPT | |
| SCHEMBL3555928 | 0.78 | TSHR (0.34) | TP53TSHRARMAPTBRD9 | |
| SCHEMBL8936370 | 0.78 | MEN1 (0.39) | MCL1TP53TSHRMAPT | |
| SCHEMBL13693064 | 0.78 | PTGS1 (0.37) | ARMAPTBRD9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0489480-A1 | Uracil derivatives and herbicides containing the same as active ingredient | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1992-06-10 | — | — | EP | claimed |
| JP-5017453-A | — | — | None | — | — | JP | disclosed |
| US-5990044-A | Selective herbicides based on aryl uracils | BAYER AKTIENGESELLSCHAFT (DE) | 1999-11-23 | — | — | US | disclosed |
| JP-H0517453-A | URACIL DERIVATIVE AND HERBICIDE | NISSAN CHEM IND LTD | 1993-01-26 | — | — | JP | disclosed |
| US-5154755-A | Uracil derivatives and herbicides containing the same as active ingredient | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1992-10-13 | — | — | US | disclosed |
| EP-0489480-A1 | Uracil derivatives and herbicides containing the same as active ingredient | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1992-06-10 | — | — | EP | disclosed |