Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 5/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | FLT1 | P17948 | 1/20 | 0.37 |
| ▸ | FLT4 | P35916 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8702165 | 1.00 | ALDH1A1 (0.44) | ALDH1A1GLAPOLBCYP11B1CYP11B2 | |
| SCHEMBL4770768 | 0.85 | ALDH1A1 (0.46) | ALDH1A1GLAPOLBCYP11B1CYP11B2 | |
| SCHEMBL10516101 | 0.85 | GLA (0.59) | ALDH1A1GLAPOLBCYP11B1CYP11B2 | |
| SCHEMBL4770761 | 0.85 | ALDH1A1 (0.46) | ALDH1A1GLAPOLBCYP11B1CYP11B2 | |
| SCHEMBL23273666 | 0.83 | DGAT1 (0.47) | ALDH1A1CYP11B1CYP11B2LMNAFLT1 | |
| SCHEMBL22774760 | 0.83 | DGAT1 (0.47) | ALDH1A1CYP11B1CYP11B2LMNAFLT1 | |
| SCHEMBL22774758 | 0.83 | DGAT1 (0.47) | ALDH1A1CYP11B1CYP11B2LMNAFLT1 | |
| SCHEMBL10475316 | 0.83 | MEN1 (0.47) | ALDH1A1GLAPOLBCYP11B1CYP11B2 | |
| SCHEMBL3411087 | 0.83 | MEN1 (0.47) | ALDH1A1GLAPOLBCYP11B1CYP11B2 | |
| SCHEMBL3411086 | 0.83 | MEN1 (0.47) | ALDH1A1GLAPOLBCYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5763450-A | BACTERICIDES; TREATMENT OF INFECTIOUS DISEASES | HOFFMANN-LA ROCHE INC. (US) | 1998-06-09 | — | — | US | disclosed |