Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 2/20 | 0.44 |
| ▸ | CES1 | P23141 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 7/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | FNTA | P49354 | 1/20 | 0.39 |
| ▸ | FNTB | P49356 | 1/20 | 0.39 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8699801 | 1.00 | KDM4E (0.44) | KDM4EMEN1RECQLKMT2ACES2 | |
| SCHEMBL1119165 | 0.81 | CES2 (0.56) | KDM4EMEN1RECQLKMT2ACES2 | |
| SCHEMBL3477218 | 0.79 | KDM4E (0.45) | KDM4EMEN1RECQLKMT2ACES2 | |
| SCHEMBL643462 | 0.78 | KMT2A (0.63) | KDM4EMEN1RECQLKMT2ACES2 | |
| SCHEMBL9815566 | 0.77 | KDM4E (0.44) | KDM4EMEN1RECQLKMT2ACES2 | |
| SCHEMBL29287447 | 0.77 | ZDHHC2 (0.46) | KDM4EMEN1RECQLKMT2ACES2 | |
| SCHEMBL372285 | 0.77 | THRB (0.46) | MEN1KMT2ACES2CES1ZDHHC2 | |
| SCHEMBL3152400 | 0.77 | CES2 (0.57) | CES2CES1ZDHHC2FAAH | |
| Toluene SCHEMBL27972648 | 0.76 | CES2 (0.50) | KDM4EMEN1RECQLKMT2ACES2 | |
| Bromide SCHEMBL28850559 | 0.76 | KMT2A (0.61) | KDM4EMEN1RECQLKMT2ACES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998049128-A1 | PROCESS FOR PREPARING A (HETERO)AROMATIC OLEFIN | DSM N.V. (NL) | 1998-11-05 | — | — | WO | disclosed |