SCHEMBL8708804

SCHEMBL8708804

CCCC(=O)NCCc1c(OC)ccc2ccccc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MTNR1A P48039 1/20 0.61
MTNR1B P49286 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8871823 0.94 MTNR1A (0.58) MTNR1AMTNR1B
SCHEMBL3915704 0.91 MTNR1A (0.73) MTNR1AMTNR1B
SCHEMBL8186004 0.85 MTNR1A (0.61) MTNR1AMTNR1B
SCHEMBL8705200 0.81 MTNR1A (0.58) MTNR1AMTNR1B
SCHEMBL8873933 0.81 MTNR1A (0.58) MTNR1AMTNR1B
SCHEMBL8989464 0.80 MTNR1A (0.58) MTNR1AMTNR1B
SCHEMBL8883733 0.80 MTNR1A (0.57) MTNR1A
SCHEMBL28387488 0.79 NCEH1 (0.60)
SCHEMBL3406179 0.78 KMT2A (0.53)
SCHEMBL30726485 0.78 KMT2A (0.53)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5708020-A FOR TREATING SLEEP DISORDERS ADIR ET COMPAGNIE (FR) 1998-01-13 US disclosed
US-5604261-A HAVING HYDROXYL/ALKOXYL GROUP ORTHO TO AMIDE GROUP ON PHENYL RING; HIGH MELATONIN RECEPTOR AFFINITY ADIR ET COMPAGNIE (FR) 1997-02-18 US disclosed
US-5554642-A USE TO TREAT MAMMALS AFFLICTED WITH SLEEP DISORDERS ADIR ET COMPAGNIE (FR) 1996-09-10 US disclosed
EP-0591057-B1 Arylalkyl(thio)amides with melatonine receptor selectivity and process for their preparation ADIR (FR) 1996-07-10 EP disclosed
US-5464872-A Sleep disorders ADIR ET COMPAGNIE (FR) 1995-11-07 US disclosed
EP-0591057-A1 Arylalkyl(thio)amides with melatonine receptor selectivity and process for their preparation ADIR ET COMPAGNIE (FR) 1994-04-06 EP disclosed