SCHEMBL8705272

SCHEMBL8705272

CCCN[C@H]1C[C@H](CCCOC)S(=O)(=O)c2sc(S(N)(=O)=O)cc21

nearest known ligand 0.85

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CA2 P00918 17/20 0.85
CA1 P00915 3/20 0.57
CA12 O43570 2/20 0.57
CA4 P22748 2/20 0.57
CA6 P23280 2/20 0.57
CA5A P35218 2/20 0.57
CA7 P43166 2/20 0.57
CA9 Q16790 2/20 0.57
CA13 Q8N1Q1 2/20 0.57
CA14 Q9ULX7 2/20 0.57
CA5B Q9Y2D0 2/20 0.57
LMNA P02545 2/20 0.57
CA3 P07451 1/20 0.57
AR P10275 1/20 0.57
TSHR P16473 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8705268 1.00 CA2 (0.85) CA2CA1CA12CA4CA6
SCHEMBL8793591 1.00 CA2 (0.85) CA2CA1CA12CA4CA6
Hydrochloric Acid SCHEMBL9329594 0.99 CA2 (0.84) CA2CA1CA12CA4CA6
SCHEMBL8794650 0.96 CA2 (0.79) CA2CA1CA12CA4CA6
SCHEMBL8794424 0.94 CA2 (0.76) CA2CA1CA12CA4CA6
SCHEMBL8792791 0.92 CA2 (1.00) CA2CA1CA12CA4CA6
Hydrochloric Acid SCHEMBL9327510 0.91 CA2 (0.98) CA2CA1CA12CA4CA6
SCHEMBL8793668 0.90 CA2 (0.69) CA2CA1CA12CA4CA6
SCHEMBL8793403 0.89 CA2 (0.67) CA2CA1CA12CA4CA6
SCHEMBL8793532 0.89 CA2 (0.68) CA2CA1CA12CA4CA6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0625903-B1 TOPICAL ANTIGLAUCOMA COMPOSITIONS COMPRISING CARBONIC ANHYDRASE INHIBITORS AND BETA-BLOCKERS ALCON LAB INC (US) 1998-08-12 EP claimed
EP-0660703-A1 TOPICAL CARBONIC ANHYDRASE INHIBITOR COMPOSITION ALCON LABORATORIES, INC. (US) 1995-07-05 EP claimed
EP-0625903-A1 TOPICAL ANTIGLAUCOMA COMPOSITIONS COMPRISING CARBONIC ANHYDRASE INHIBITORS AND BETA-BLOCKERS ALCON LABORATORIES, INC. (US) 1994-11-30 EP claimed
WO-1994006411-A1 TOPICAL CARBONIC ANHYDRASE INHIBITOR COMPOSITION ALCON LABORATORIES, INC. (US) 1994-03-31 WO claimed
WO-1993016701-A2 TOPICAL ANTIGLAUCOMA COMPOSITIONS COMPRISING CARBONIC ANHYDRASE INHIBITORS AND BETA-BLOCKERS ALCON LABORATORIES, INC. (US) 1993-09-02 WO claimed
EP-4714407-A2 DEVICES TO PROVIDE HANDS FREE SCLERAL DEPRESSION DURING OPHTHALMIC PROCEDURES Alcon Inc. (CH) 2026-03-25 EP disclosed
EP-3157408-B1 DEVICES TO PROVIDE HANDS FREE SCLERAL DEPRESSION DURING OPHTHALMIC PROCEDURES ALCON INC (CH) 2026-03-25 EP disclosed
US-20250057694-A1 DEVICES AND METHODS TO PROVIDE HANDS FREE SCLERAL DEPRESSION AND ILLUMINATION DURING OPHTHALMIC PROCEDURES Ganihand, LLC (US) 2025-02-20 US disclosed
US-11266395-B2 Devices and methods to provide hands free scleral depression during ophthalmic procedures Ganihand, LLC (US) 2022-03-08 US disclosed
EP-0625903-B1 TOPICAL ANTIGLAUCOMA COMPOSITIONS COMPRISING CARBONIC ANHYDRASE INHIBITORS AND BETA-BLOCKERS ALCON LAB INC (US) 1998-08-12 EP disclosed
EP-0660703-A1 TOPICAL CARBONIC ANHYDRASE INHIBITOR COMPOSITION ALCON LABORATORIES, INC. (US) 1995-07-05 EP disclosed
WO-1994006411-A1 TOPICAL CARBONIC ANHYDRASE INHIBITOR COMPOSITION ALCON LABORATORIES, INC. (US) 1994-03-31 WO disclosed