Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | HTR6 | P50406 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | FLT1 | P17948 | 1/20 | 0.41 |
| ▸ | FLT4 | P35916 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | CMA1 | P23946 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8700597 | 0.89 | PPARG (0.44) | PPARGPTGS1PTGS2HTR6KMT2A | |
| SCHEMBL8707541 | 0.88 | PPARG (0.43) | PPARGPPARAHTR6CMA1PSEN1 | |
| SCHEMBL8704328 | 0.82 | CMA1 (0.35) | PPARGPPARAPTGS1PTGS2CMA1 | |
| SCHEMBL8705100 | 0.81 | HTT (0.38) | — | |
| SCHEMBL7472814 | 0.80 | PPARG (0.51) | PPARGPPARAHTR6MEN1KMT2A | |
| SCHEMBL7465212 | 0.77 | PPARG (0.43) | PPARGPPARAPTGS1PTGS2HTR6 | |
| SCHEMBL8705102 | 0.74 | GAA (0.38) | PPARGPPARAMEN1KMT2APOLB | |
| SCHEMBL7463805 | 0.74 | KMT2A (0.40) | PPARGPPARAHTR6MEN1KMT2A | |
| SCHEMBL7465592 | 0.72 | CMA1 (0.54) | PTGS1PTGS2HTR6MEN1KMT2A | |
| Iodide SCHEMBL7467982 | 0.72 | PPARG (0.39) | PPARGPPARAPTGS1PTGS2HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5814631-A | CHYMASE INHIBITOR, CARDIVASCULAR | SUNTORY LIMITED (JP) | 1998-09-29 | — | — | US | disclosed |