Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.34 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | PPARD | Q03181 | 2/20 | 0.33 |
| ▸ | PPARA | Q07869 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7467945 | 0.84 | AKR1B1 (0.39) | GAAMAPTPPARGPPARDPPARA | |
| SCHEMBL7460868 | 0.82 | GAA (0.36) | GAAMAPTL3MBTL1SMN1; SMN2POLB | |
| SCHEMBL8707541 | 0.81 | PPARG (0.43) | NOD2NOD1PPARGPPARDPPARA | |
| SCHEMBL7472633 | 0.79 | MAPT (0.36) | GAAMAPTKMT2AMEN1KDM4E | |
| SCHEMBL8707152 | 0.78 | MAT2A (0.43) | GAAMAPTL3MBTL1KMT2AMEN1 | |
| SCHEMBL7472700 | 0.78 | CMA1 (0.55) | GAAMAPTL3MBTL1KMT2APKM | |
| SCHEMBL7472835 | 0.78 | SMN1; SMN2 (0.43) | NOD2NOD1MAPTL3MBTL1SMN1; SMN2 | |
| Iodide SCHEMBL7464172 | 0.78 | GAA (0.35) | GAANOD2NOD1KDM4EHPGD | |
| SCHEMBL8700597 | 0.76 | PPARG (0.44) | NOD2NOD1MAPTPPARGPPARD | |
| SCHEMBL7472637 | 0.76 | MEN1 (0.40) | GAAMAPTL3MBTL1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5814631-A | CHYMASE INHIBITOR, CARDIVASCULAR | SUNTORY LIMITED (JP) | 1998-09-29 | — | — | US | disclosed |