Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MAT2A | P31153 | 8/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8707541 | 0.88 | PPARG (0.43) | HTTTSHR | |
| SCHEMBL8700597 | 0.83 | PPARG (0.44) | HTTNPSR1TSHR | |
| SCHEMBL8705373 | 0.81 | PPARG (0.47) | — | |
| SCHEMBL8704328 | 0.80 | CMA1 (0.35) | MCL1 | |
| SCHEMBL7468725 | 0.79 | HTT (0.38) | HTTUSP2NPSR1MAT2ASMN1; SMN2 | |
| SCHEMBL7472775 | 0.79 | AKR1B1 (0.44) | HTTUSP2NPSR1MAT2ASMN1; SMN2 | |
| SCHEMBL7461621 | 0.78 | KDM4E (0.38) | HTTUSP2NPSR1MAT2APRMT5 | |
| SCHEMBL8705102 | 0.76 | GAA (0.38) | USP2NPSR1SMN1; SMN2 | |
| SCHEMBL7468729 | 0.75 | MAPT (0.46) | SMN1; SMN2TSHR | |
| SCHEMBL7457272 | 0.75 | NOD1 (0.37) | HTTUSP2NPSR1MAT2APRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5814631-A | CHYMASE INHIBITOR, CARDIVASCULAR | SUNTORY LIMITED (JP) | 1998-09-29 | — | — | US | disclosed |