Styrene

Styrene

SCHEMBL8705408

C=C(C)C(=O)O.C=C(C)C(=O)OC.C=CC(=O)OC.C=Cc1ccccc1

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.43
TSHR P16473 1/20 0.40
AKR1C3 P42330 1/20 0.37
ELANE P08246 1/20 0.36
MAPT P10636 3/20 0.35
LMNA P02545 2/20 0.35
KDM4E B2RXH2 2/20 0.35
HTT P42858 2/20 0.35
POLB P06746 1/20 0.35
THRB P10828 1/20 0.34
GLA P06280 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
MEN1 O00255 1/20 0.33
HPGD P15428 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL4882975 0.97 ALDH1A1 (0.46) ALDH1A1TSHRAKR1C3ELANEMAPT
Styrene SCHEMBL7571018 0.94 ALDH1A1 (0.45) ALDH1A1TSHRAKR1C3MAPTLMNA
Styrene SCHEMBL244050 0.93 ALDH1A1 (0.50) ALDH1A1TSHRAKR1C3ELANEMAPT
Styrene SCHEMBL3369533 0.91 ALDH1A1 (0.46) ALDH1A1TSHRAKR1C3ELANEMAPT
Styrene SCHEMBL9482566 0.90 ALDH1A1 (0.44) ALDH1A1TSHRAKR1C3ELANEMAPT
Styrene SCHEMBL11581751 0.90 ALDH1A1 (0.47) ALDH1A1TSHRAKR1C3ELANEMAPT
Styrene SCHEMBL9639818 0.89 ALDH1A1 (0.54) ALDH1A1TSHRAKR1C3ELANEMAPT
Styrene SCHEMBL678464 0.89 ALDH1A1 (0.54) ALDH1A1TSHRAKR1C3ELANEMAPT
Styrene SCHEMBL8576362 0.89 ALDH1A1 (0.54) ALDH1A1TSHRAKR1C3ELANEMAPT
Styrene SCHEMBL35776 0.89 ALDH1A1 (0.54) ALDH1A1TSHRAKR1C3ELANEMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0566353-B1 Photopolymerizable composition MITSUBISHI RAYON CO (JP) 1998-08-19 EP disclosed