Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | GAA | P10253 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8709118 | 1.00 | KDM4E (0.46) | KDM4EMEN1KMT2AALDH1A1GAA | |
| SCHEMBL8705458 | 1.00 | KDM4E (0.46) | KDM4EMEN1KMT2AALDH1A1GAA | |
| SCHEMBL8705477 | 0.88 | KDM4E (0.47) | KDM4EMEN1KMT2AALDH1A1GAA | |
| SCHEMBL8709010 | 0.88 | KDM4E (0.46) | KDM4EMEN1KMT2AALDH1A1GAA | |
| SCHEMBL8711495 | 0.87 | KDM4E (0.43) | KDM4EMEN1KMT2AALDH1A1GAA | |
| SCHEMBL8711497 | 0.87 | KDM4E (0.43) | KDM4EMEN1KMT2AALDH1A1GAA | |
| SCHEMBL8707133 | 0.79 | PDE4A (0.38) | MEN1KMT2AALDH1A1GAA | |
| SCHEMBL8705344 | 0.79 | PDE4A (0.38) | MEN1KMT2AALDH1A1GAA | |
| SCHEMBL8709379 | 0.78 | KDM4E (0.43) | KDM4EMEN1KMT2AALDH1A1GAA | |
| SCHEMBL4105083 | 0.74 | ADORA1 (0.41) | KDM4EMEN1KMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0619316-B1 | Xanthine derivatives | KYOWA HAKKO KOGYO KK (JP) | 1998-08-12 | — | — | EP | disclosed |
| EP-0619316-A1 | Xanthine derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1994-10-12 | — | — | EP | disclosed |