Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.47 |
| ▸ | MEN1 | O00255 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | GAA | P10253 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.39 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.39 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8705458 | 0.88 | KDM4E (0.46) | KDM4EMEN1KMT2AALDH1A1GAA | |
| SCHEMBL8705454 | 0.88 | KDM4E (0.46) | KDM4EMEN1KMT2AALDH1A1GAA | |
| SCHEMBL8709118 | 0.88 | KDM4E (0.46) | KDM4EMEN1KMT2AALDH1A1GAA | |
| SCHEMBL8709010 | 0.88 | KDM4E (0.46) | KDM4EMEN1KMT2AALDH1A1GAA | |
| SCHEMBL4105083 | 0.85 | ADORA1 (0.41) | KDM4EMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL8709379 | 0.85 | KDM4E (0.43) | KDM4EMEN1KMT2AALDH1A1GAA | |
| SCHEMBL8711497 | 0.84 | KDM4E (0.43) | KDM4EMEN1KMT2AALDH1A1GAA | |
| SCHEMBL8711495 | 0.84 | KDM4E (0.43) | KDM4EMEN1KMT2AALDH1A1GAA | |
| SCHEMBL7279899 | 0.83 | ADORA1 (0.44) | MEN1KMT2AALDH1A1GAAMAPT | |
| SCHEMBL7279799 | 0.81 | CNR2 (0.40) | KDM4EMEN1KMT2AALDH1A1ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0619316-B1 | Xanthine derivatives | KYOWA HAKKO KOGYO KK (JP) | 1998-08-12 | — | — | EP | disclosed |
| EP-0711772-A1 | PROCESS FOR PRODUCING XANTHINE DERIVATIVE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1996-05-15 | — | — | EP | disclosed |
| EP-0619316-A1 | Xanthine derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1994-10-12 | — | — | EP | disclosed |