Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.61 |
| ▸ | HPGD | P15428 | 8/20 | 0.61 |
| ▸ | HTT | P42858 | 5/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.59 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 3/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 6/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9407637 | 0.94 | HPGD (0.62) | ALDH1A1HPGDHTTKDM4EHSD17B10 | |
| SCHEMBL9407626 | 0.93 | ALDH1A1 (0.61) | ALDH1A1HPGDHTTKDM4EHSD17B10 | |
| SCHEMBL9407618 | 0.92 | ALDH1A1 (0.61) | ALDH1A1HPGDHTTKDM4EHSD17B10 | |
| SCHEMBL9407620 | 0.92 | ALDH1A1 (0.61) | ALDH1A1HPGDHTTKDM4EHSD17B10 | |
| SCHEMBL9407622 | 0.90 | ALDH1A1 (0.59) | ALDH1A1HPGDHTTKDM4EHSD17B10 | |
| SCHEMBL9223089 | 0.89 | KDM4E (0.74) | ALDH1A1HPGDHTTKDM4EHSD17B10 | |
| SCHEMBL10739914 | 0.83 | KDM4E (0.70) | ALDH1A1HPGDHTTKDM4EHSD17B10 | |
| SCHEMBL312380 | 0.83 | KDM4E (0.84) | ALDH1A1HPGDHTTKDM4EHSD17B10 | |
| SCHEMBL312663 | 0.83 | KDM4E (0.70) | ALDH1A1HPGDHTTKDM4EHSD17B10 | |
| SCHEMBL11185030 | 0.83 | KDM4E (0.71) | ALDH1A1HPGDHTTKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0610896-A1 | Quinolonecarboxylic acid derivatives as antibacterials | Senju Pharmaceutical Co., Ltd. (JP) | 1994-08-17 | — | — | EP | claimed |
| US-5753658-A | FOR TREATMENT OF BACTERIAL INFECTIONS | SENJU PHARMACEUTICAL CO., LTD. (JP) | 1998-05-19 | — | — | US | disclosed |
| EP-0610896-A1 | Quinolonecarboxylic acid derivatives as antibacterials | Senju Pharmaceutical Co., Ltd. (JP) | 1994-08-17 | — | — | EP | disclosed |