Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 6/20 | 0.67 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.56 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.56 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.56 |
| ▸ | HTR1A | P08908 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | HTR6 | P50406 | 2/20 | 0.52 |
| ▸ | TYR | P14679 | 1/20 | 0.52 |
| ▸ | DRD2 | P14416 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | DRD3 | P35462 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8702916 | 0.85 | HTR7 (0.57) | HTR7ADRA1AADRA1DADRA1BHTR1A | |
| Hydrochloric Acid SCHEMBL8707962 | 0.85 | HTR7 (0.52) | HTR7ADRA1AADRA1DADRA1BHTR1A | |
| Hydrochloric Acid SCHEMBL8706156 | 0.82 | HTR7 (0.57) | HTR7ADRA1AADRA1DADRA1BHTR1A | |
| SCHEMBL2984584 | 0.80 | HTR7 (1.00) | HTR7 | |
| SCHEMBL8704958 | 0.80 | HTR7 (0.52) | HTR7ADRA1AADRA1DADRA1BHTR1A | |
| Oxalic Acid SCHEMBL2984158 | 0.78 | HTR7 (0.91) | HTR7DRD2ALDH1A1DRD3KDM4E | |
| SCHEMBL8706092 | 0.78 | HTR7 (0.52) | HTR7ADRA1AADRA1DADRA1BHTR1A | |
| Hydrochloric Acid SCHEMBL8705245 | 0.76 | HTR7 (0.51) | HTR7ADRA1AADRA1DADRA1BHTR1A | |
| SCHEMBL8702050 | 0.75 | HTR7 (0.53) | HTR7HTR1AMEN1KMT2AHTR6 | |
| SCHEMBL8730046 | 0.75 | HTR7 (0.55) | HTR7ADRA1AADRA1DADRA1BHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998002432-A1 | BICYCLIC COMPOUNDS FOR CONTROLLING MICTURITION | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-01-22 | — | — | WO | disclosed |