Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 4/20 | 0.55 |
| ▸ | DRD2 | P14416 | 8/20 | 0.52 |
| ▸ | DRD3 | P35462 | 6/20 | 0.52 |
| ▸ | DRD4 | P21917 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | HTR1A | P08908 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8705641 | 0.75 | HTR7 (0.67) | HTR7DRD2DRD3MEN1HTR1A | |
| SCHEMBL10641480 | 0.71 | DRD2 (0.61) | HTR7DRD2DRD3DRD4MEN1 | |
| SCHEMBL2984584 | 0.71 | HTR7 (1.00) | HTR7 | |
| SCHEMBL10641064 | 0.70 | DRD2 (0.67) | HTR7DRD2DRD3DRD4MEN1 | |
| SCHEMBL10642850 | 0.70 | DRD2 (0.70) | HTR7DRD2DRD3DRD4MEN1 | |
| SCHEMBL6158309 | 0.70 | HTR7 (0.88) | HTR7 | |
| SCHEMBL6526368 | 0.70 | DRD2 (0.85) | HTR7DRD2DRD3MEN1HTR1A | |
| SCHEMBL8854936 | 0.69 | HTR1A (0.76) | HTR7DRD2DRD3MEN1HTR1A | |
| Hydrochloric Acid SCHEMBL8702916 | 0.69 | HTR7 (0.57) | HTR7DRD2DRD3MEN1HTR1A | |
| SCHEMBL11825044 | 0.69 | ADRA1A (0.81) | HTR7DRD2DRD3MEN1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0624584-B1 | Piperazine derivatives useful as calmodulin inhibitors | DAIICHI SEIYAKU CO (JP) | 1998-08-19 | — | — | EP | disclosed |
| EP-0624584-A1 | Piperazine derivatives useful as calmodolin inhibitors | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1994-11-17 | — | — | EP | disclosed |