SCHEMBL8705677

SCHEMBL8705677

[C-]#[N+]Cc1noc(C(C)(C)C)n1

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20365263 0.75 AOC3 (0.38) CNR2
SCHEMBL91618 0.75 AOC3 (0.32) CNR2
SCHEMBL16232109 0.74 GRM5 (0.37)
SCHEMBL2869278 0.74 NOTUM (0.40) CNR2
SCHEMBL7279535 0.74
SCHEMBL478959 0.74 CNR2 (0.33) CNR2
SCHEMBL2869276 0.74 AOC3 (0.31) CNR2
SCHEMBL10025201 0.74 AOC3 (0.31) CNR2
SCHEMBL10058001 0.72 ALDH1A1 (0.42) CNR2
SCHEMBL21325031 0.71 CXCR3 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0833638-A1 USE OF IMIDAZO 1,5-a]QUINOLONES AS NEUROPROTECTIVE AGENTS PHARMACIA & UPJOHN COMPANY (US) 1998-04-08 EP disclosed
US-5668282-A 4,5-cyclicimidazo[1,5-A]quinoxalines PHARMACIA & UPJOHN COMPANY (US) 1997-09-16 US disclosed
US-5574038-A 5,6-cyclicimidazo [1,5-a] Quinoxalines THE UPJOHN COMPANY (US) 1996-11-12 US disclosed
US-5541324-A Imidazo[1,5-A]quinoxalines THE UPJOHN COMPANY (US) 1996-07-30 US disclosed
WO-1992022552-A1 IMIDAZO[1,5-a]QUINOXALINES THE UPJOHN COMPANY (US) 1992-12-23 WO disclosed