Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.32 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.32 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | SPOP | O43791 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL8705758 | 0.94 | HDAC1 (0.33) | HDAC1 | |
| Trifluoroacetic Acid SCHEMBL8705789 | 0.94 | HDAC1 (0.33) | HDAC1 | |
| Trifluoroacetic Acid SCHEMBL8701852 | 0.93 | POLB (0.32) | HDAC1POLBMAPTPKMHTT | |
| Trifluoroacetic Acid SCHEMBL5501776 | 0.93 | DRD2 (0.32) | HDAC1POLBMAPTPKMHTT | |
| Trifluoroacetic Acid SCHEMBL5501760 | 0.93 | DRD2 (0.32) | HDAC1POLBMAPTPKMHTT | |
| Trifluoroacetic Acid SCHEMBL5507641 | 0.91 | HDAC1 (0.34) | HDAC1POLBMAPTPKMHTT | |
| Trifluoroacetic Acid SCHEMBL8705894 | 0.91 | POLB (0.33) | HDAC1POLBMAPTPKMHTT | |
| Trifluoroacetic Acid SCHEMBL8705695 | 0.91 | HDAC1 (0.31) | HDAC1POLBMAPTPKMHTT | |
| Trifluoroacetic Acid SCHEMBL5507637 | 0.91 | HDAC1 (0.34) | HDAC1POLBMAPTPKMHTT | |
| Trifluoroacetic Acid SCHEMBL8701786 | 0.91 | HDAC1 (0.34) | HDAC1POLBMAPTPKMHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0838465-A1 | Pyridinium-substituted (lactamylvinyl)cephalosporin derivatives, their preparation and their use as antibiotics | F. HOFFMANN-LA ROCHE AG (CH) | 1998-04-29 | — | — | EP | disclosed |