Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA3 | P07451 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.40 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | CGAS | Q8N884 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8706213 | 0.87 | HTT (0.47) | HTTMAPTAAK1NR1I2 | |
| SCHEMBL8704442 | 0.86 | AAK1 (0.45) | HTTMAPTAAK1CGASTSHR | |
| SCHEMBL8701815 | 0.86 | HTT (0.43) | HTTMAPTAAK1ALDH1A1 | |
| SCHEMBL8700673 | 0.85 | HTT (0.42) | HTTMAPTNPSR1AAK1MEN1 | |
| SCHEMBL8703295 | 0.83 | HTT (0.41) | HTTMAPTNPSR1AAK1ALDH1A1 | |
| SCHEMBL8704888 | 0.83 | HTT (0.41) | HTTMAPTNPSR1AAK1ALDH1A1 | |
| SCHEMBL8705466 | 0.83 | HTT (0.41) | HTTMAPTAAK1KMT2AALDH1A1 | |
| SCHEMBL8700122 | 0.83 | ALDH1A1 (0.42) | HTTMAPTAAK1MEN1KMT2A | |
| SCHEMBL8705327 | 0.83 | HTT (0.41) | HTTMAPTNPSR1AAK1MEN1 | |
| SCHEMBL8703972 | 0.82 | MAPT (0.56) | HTTMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753680-A | Heterocyclyl-benzoylguanidines | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-05-19 | — | — | US | disclosed |