Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.32 |
| ▸ | DRD1 | P21728 | 2/20 | 0.32 |
| ▸ | DRD4 | P21917 | 2/20 | 0.32 |
| ▸ | DRD5 | P21918 | 2/20 | 0.32 |
| ▸ | DRD3 | P35462 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4538423 | 0.71 | — | — | |
| SCHEMBL25228428 | 0.65 | — | — | |
| SCHEMBL9640284 | 0.63 | CHRM2 (0.46) | — | |
| SCHEMBL3161104 | 0.62 | — | — | |
| SCHEMBL3485175 | 0.62 | DRD3 (0.42) | DRD2DRD1DRD4DRD3 | |
| Hydrochloric Acid SCHEMBL4152474 | 0.61 | DRD3 (0.41) | DRD2DRD1DRD4DRD3 | |
| SCHEMBL7459966 | 0.60 | — | — | |
| SCHEMBL12192065 | 0.59 | PTGS2 (0.31) | — | |
| SCHEMBL15758249 | 0.58 | SLC6A9 (0.30) | — | |
| SCHEMBL19257936 | 0.58 | SLC6A9 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828513-A2 | COMBINATIONS FOR THE TREATMENT OF PARKINSONISM CONTAINING SELECTIVE NMDA ANTAGONISTS | PFIZER INC. (US) | 1998-03-18 | — | — | EP | disclosed |
| WO-1996037226-A2 | COMBINATIONS FOR THE TREATMENT OF PARKINSONISM CONTAINING SELECTIVE NMDA ANTAGONISTS | PFIZER INC. (US) | 1996-11-28 | — | — | WO | disclosed |