Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.53 |
| ▸ | RAB9A | P51151 | 6/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | FLT3 | P36888 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA3 | P07451 | 1/20 | 0.45 |
| ▸ | CA4 | P22748 | 1/20 | 0.45 |
| ▸ | CA6 | P23280 | 1/20 | 0.45 |
| ▸ | CA5A | P35218 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14471296 | 0.85 | ALDH1A1 (0.55) | NPC1RAB9AMEN1KMT2ATSHR | |
| SCHEMBL10368234 | 0.83 | FLT3 (0.52) | NPC1RAB9AMEN1KMT2ATSHR | |
| SCHEMBL11922829 | 0.77 | TAS1R3 (0.53) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL5515850 | 0.75 | ALDH1A1 (0.52) | NPC1RAB9AMEN1KMT2ATSHR | |
| SCHEMBL28591305 | 0.73 | CYP2D6 (0.57) | NPC1RAB9AALDH1A1LMNATHRB | |
| SCHEMBL4047365 | 0.73 | CYP2D6 (0.57) | NPC1RAB9AALDH1A1LMNATHRB | |
| SCHEMBL17969087 | 0.73 | CYP2D6 (0.49) | RAB9AALDH1A1LMNATHRBFLT3 | |
| SCHEMBL17599990 | 0.73 | CYP2A6 (0.45) | NPC1RAB9AMEN1KMT2ATSHR | |
| SCHEMBL16746791 | 0.73 | ALDH1A1 (0.46) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL162882 | 0.73 | NPC1 (0.52) | NPC1RAB9AALDH1A1LMNATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-10237089-A | — | — | None | — | — | JP | disclosed |
| JP-H10237089-A | PROPIOPHENONE DERIVATIVE AND ITS PRODUCTION | TANABE SEIYAKU CO LTD | 1998-09-08 | — | — | JP | disclosed |