Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R38 | P59533 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7667200 | 0.86 | TSHR (0.39) | TAS2R38ALDH1A1HSD17B10PTGS2HPGD | |
| SCHEMBL27901765 | 0.85 | MGAM (0.48) | TAS2R38ALDH1A1HPGDMGAMGAA | |
| SCHEMBL28956119 | 0.84 | — | — | |
| SCHEMBL27232988 | 0.82 | — | — | |
| SCHEMBL28172315 | 0.82 | TSHR (0.44) | TAS2R38GAA | |
| SCHEMBL27781159 | 0.82 | — | — | |
| SCHEMBL28265511 | 0.80 | TAS2R38 (0.36) | TAS2R38ALDH1A1HPGDMGAMGAA | |
| SCHEMBL27989359 | 0.77 | — | — | |
| SCHEMBL13734020 | 0.77 | TSHR (0.37) | MGAMGAASIMGAM2 | |
| SCHEMBL10393977 | 0.77 | TAS2R38 (0.39) | TAS2R38ALDH1A1HSD17B10PTGS2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998015545-A1 | NEW SEROTONIN 5-HT1F AGONISTS | ELI LILLY AND COMPANY (US) | 1998-04-16 | — | — | WO | disclosed |