SCHEMBL7667200

SCHEMBL7667200

NC(=S)NOC(=O)CCC(=O)ONC(N)=S

nearest known ligand 0.39

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.39
TAS2R38 P59533 1/20 0.35
KDM4E B2RXH2 1/20 0.33
LMNA P02545 1/20 0.33
ALDH1A1 P00352 2/20 0.32
HSD17B10 Q99714 2/20 0.32
PTGS2 P35354 1/20 0.32
HPGD P15428 1/20 0.32
CYP1A2 P05177 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28172315 0.90 TSHR (0.44) TSHRTAS2R38CYP1A2
SCHEMBL8707689 0.86 TAS2R38 (0.36) TAS2R38ALDH1A1HSD17B10PTGS2HPGD
SCHEMBL28956119 0.82
SCHEMBL27781159 0.80
SCHEMBL27232988 0.80
SCHEMBL8948098 0.80 DGKA (0.50) TSHRLMNACYP1A2
SCHEMBL28265511 0.78 TAS2R38 (0.36) TAS2R38ALDH1A1HPGD
SCHEMBL27901765 0.78 MGAM (0.48) TAS2R38KDM4ELMNAALDH1A1HPGD
SCHEMBL20898404 0.78 TSHR (0.43) TSHRKDM4ELMNAALDH1A1HSD17B10
SCHEMBL1071160 0.76 TSHR (0.41) TSHRKDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1269899-C Vinglpyrrolidone polymer composition NIPPON CATALYTIC CHEM IND (JP) 2006-08-16 CN disclosed
CN-1536018-A Vinglpyrrolidone polymer composition 株式会社日本触媒 2004-10-13 CN disclosed
CN-1152066-C Method for preserving vinylpyrrolidone polymer 株式会社日本触媒 2004-06-02 CN disclosed
US-6498231-B2 HEAT RESISTANCE AND STORAGE STABILITY NIPPON SHOKUBAI CO., LTD. (JP) 2002-12-24 US disclosed
CN-1271739-A Vinyl pyrrolidone polymer and its stabilizing and preserving method NIPPON CATALYTIC CHEM IND (JP) 2000-11-01 CN disclosed