Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 2/20 | 0.37 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 14/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 12/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.31 |
| ▸ | CTSK | P43235 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8683250 | 0.98 | PRKCA (0.38) | PRKCAPRKCDL3MBTL1ALDH1A1SLC6A3 | |
| SCHEMBL8706192 | 0.90 | HPGD (0.32) | L3MBTL1CTSKMEN1KMT2ATDP1 | |
| SCHEMBL8683121 | 0.89 | PRKCA (0.40) | PRKCAPRKCDL3MBTL1ALDH1A1CTSK | |
| SCHEMBL8682180 | 0.88 | KDM4E (0.30) | L3MBTL1 | |
| SCHEMBL8683212 | 0.88 | L3MBTL1 (0.37) | PRKCAPRKCDL3MBTL1ALDH1A1MEN1 | |
| SCHEMBL8680800 | 0.88 | L3MBTL1 (0.37) | PRKCAPRKCDL3MBTL1ALDH1A1MEN1 | |
| SCHEMBL8681300 | 0.88 | L3MBTL1 (0.37) | PRKCAPRKCDL3MBTL1ALDH1A1MEN1 | |
| SCHEMBL8680967 | 0.88 | L3MBTL1 (0.37) | PRKCAPRKCDL3MBTL1ALDH1A1MEN1 | |
| SCHEMBL8681220 | 0.88 | L3MBTL1 (0.37) | PRKCAPRKCDL3MBTL1ALDH1A1MEN1 | |
| SCHEMBL8686125 | 0.88 | PRKCA (0.37) | PRKCAPRKCDL3MBTL1ALDH1A1CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0844000-A1 | Use of alpha, omega-diarylalkane derivatives in the treatment and prevention of psychosis | SANKYO COMPANY LIMITED (JP) | 1998-05-27 | — | — | EP | disclosed |
| US-5556864-A | TREATMENT OF CIRCULATORY DISEASES AND PSYCHOSIS | SANKYO COMPANY, LIMITED (JP) | 1996-09-17 | — | — | US | disclosed |
| EP-0600717-A1 | Phenoxyalkylamines, -pyrrolidines and -piperidines for the treatment and prevention of circulatory diseases and psychosis | SANKYO COMPANY LIMITED (JP) | 1994-06-08 | — | — | EP | disclosed |