Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | TOP2A | P11388 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GPR88 | Q9GZN0 | 3/20 | 0.32 |
| ▸ | KLK7 | P49862 | 1/20 | 0.32 |
| ▸ | FNTA | P49354 | 1/20 | 0.32 |
| ▸ | FNTB | P49356 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8325294 | 0.82 | OPRK1 (0.37) | OPRK1MEN1KMT2AGAAL3MBTL1 | |
| SCHEMBL8705028 | 0.82 | OPRK1 (0.42) | OPRK1MEN1KMT2AGPR88KLK7 | |
| SCHEMBL7738582 | 0.74 | CYP1A2 (0.35) | MEN1KMT2ATOP2AGAA | |
| SCHEMBL7739318 | 0.74 | CYP1A2 (0.35) | MEN1KMT2ATOP2AGAA | |
| SCHEMBL7739287 | 0.74 | CYP1A2 (0.35) | MEN1KMT2ATOP2AGAA | |
| SCHEMBL7739395 | 0.74 | CYP1A2 (0.35) | MEN1KMT2ATOP2AGAA | |
| SCHEMBL7738017 | 0.74 | CYP1A2 (0.35) | MEN1KMT2ATOP2AGAA | |
| SCHEMBL7739282 | 0.72 | FKBP1A (0.34) | TOP2AGAA | |
| SCHEMBL5673208 | 0.69 | FKBP1A (0.37) | TOP2A | |
| SCHEMBL10380887 | 0.68 | SMYD2 (0.39) | OPRK1KLK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750549-A | ANTIINFLAMMATORY AGENTS OR ANALGESICS | MERCK & CO., INC. (US) | 1998-05-12 | — | — | US | disclosed |