Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10422636 | 0.86 | HSD17B1 (0.41) | — | |
| SCHEMBL10544021 | 0.76 | SMN1; SMN2 (0.38) | — | |
| SCHEMBL10564114 | 0.71 | MAPT (0.39) | — | |
| SCHEMBL10422643 | 0.70 | MEN1 (0.32) | — | |
| SCHEMBL27498168 | 0.60 | — | — | |
| SCHEMBL2406293 | 0.55 | CA12 (0.36) | ESR2 | |
| SCHEMBL2202782 | 0.55 | TTR (0.41) | — | |
| SCHEMBL16486834 | 0.55 | KDM4E (0.60) | ESR1 | |
| SCHEMBL25232771 | 0.55 | — | — | |
| SCHEMBL10528819 | 0.54 | CYP11B1 (0.36) | ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4892940-A | Aromatic naphthyl compounds, a process for their preparation and their use in human and veterinary medicine and in cosmetic compositions | L'OREAL (FR) | 1990-01-09 | — | — | US | claimed |
| US-5837725-A | Bridged bicyclic aromatic compounds and their use in modulating gene expression of retinoid receptors | SRI INTERNATIONAL (US) | 1998-11-17 | — | — | US | disclosed |
| US-4892940-A | Aromatic naphthyl compounds, a process for their preparation and their use in human and veterinary medicine and in cosmetic compositions | L'OREAL (FR) | 1990-01-09 | — | — | US | disclosed |