SCHEMBL10422643

SCHEMBL10422643

O=C=C1c2ccccc2C=CC1C(=O)O

nearest known ligand 0.32

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 1/20 0.32
LMNA P02545 1/20 0.32
BCHE P06276 1/20 0.32
POLB P06746 1/20 0.32
PTPRC P08575 1/20 0.32
MAPT P10636 1/20 0.32
THRB P10828 1/20 0.32
PKM P14618 1/20 0.32
IDO1 P14902 1/20 0.32
HPGD P15428 1/20 0.32
ALOX15 P16050 1/20 0.32
PTPN1 P18031 1/20 0.32
ACHE P22303 1/20 0.32
CES1 P23141 1/20 0.32
RECQL P46063 1/20 0.32
HSD17B10 Q99714 1/20 0.32
PTPN22 Q9Y2R2 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16554367 0.77 EDNRB (0.41) MEN1KMT2AKDM4EALDH1A1LMNA
SCHEMBL9118319 0.77 KMT2A (0.34) MEN1KMT2AKDM4EALDH1A1LMNA
SCHEMBL10544021 0.75 SMN1; SMN2 (0.38) MEN1KMT2AKDM4EALDH1A1LMNA
SCHEMBL28075589 0.73 MEN1 (0.35) MEN1KMT2AKDM4EALDH1A1LMNA
SCHEMBL63928 0.71 EDNRA (0.39) MEN1KMT2AALDH1A1EDNRBEDNRA
SCHEMBL29401941 0.71 EDNRA (0.39) MEN1KMT2AALDH1A1EDNRBEDNRA
SCHEMBL8708160 0.70 ESR1 (0.31)
Ammonia Solution, Strong SCHEMBL28107850 0.69 EDNRA (0.38) MEN1KMT2AALDH1A1EDNRBEDNRA
SCHEMBL28970647 0.69 EDNRA (0.38) MEN1KMT2AALDH1A1EDNRBEDNRA
SCHEMBL28628608 0.69 LMNA (0.30) LMNAEDNRBEDNRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4892940-A Aromatic naphthyl compounds, a process for their preparation and their use in human and veterinary medicine and in cosmetic compositions L'OREAL (FR) 1990-01-09 US disclosed