Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 12/20 | 0.48 |
| ▸ | HTR2A | P28223 | 4/20 | 0.47 |
| ▸ | HTR2B | P41595 | 4/20 | 0.47 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.45 |
| ▸ | MIF | P14174 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8713013 | 0.88 | HTR2C (0.46) | HTR2CHTR2AHTR2B | |
| SCHEMBL8707868 | 0.85 | HTR2C (0.43) | HTR2CHTR2AHTR2BPIK3CGMCHR1 | |
| SCHEMBL8707421 | 0.79 | HTR2C (0.46) | HTR2CHTR2AHTR2B | |
| SCHEMBL8708977 | 0.79 | HTR2C (0.49) | HTR2CHTR2AHTR2BPIK3CGMCHR1 | |
| SCHEMBL8707504 | 0.74 | HTR2C (0.53) | HTR2CHTR2AHTR2BPIK3CGMCHR1 | |
| SCHEMBL8710756 | 0.73 | NPC1 (0.60) | HTR2CPIK3CGMCHR1NPC1RAB9A | |
| SCHEMBL7700465 | 0.72 | PDE4B (0.44) | HTR2CHTR2AHTR2BMCHR1 | |
| SCHEMBL8708038 | 0.72 | HTR2C (0.53) | HTR2CHTR2AHTR2BPIK3CGMCHR1 | |
| SCHEMBL7695248 | 0.72 | HTR2C (0.50) | HTR2CHTR2AHTR2BMCHR1 | |
| SCHEMBL19422995 | 0.71 | LMNA (0.49) | HTR2CHTR2AHTR2BMCHR1MIF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998042666-A1 | NOVEL 3,4-DIALKOXYPHENYL DERIVATIVES AND THE USE THEREOF | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 1998-10-01 | — | — | WO | disclosed |