Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | HTR2C | P28335 | 5/20 | 0.49 |
| ▸ | UGCG | Q16739 | 8/20 | 0.46 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.44 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8707865 | 0.89 | MAPT (0.52) | NPC1RAB9ATP53MAPTSMN1; SMN2 | |
| SCHEMBL8713322 | 0.88 | MAPT (0.51) | NPC1RAB9ATP53MAPTSMN1; SMN2 | |
| SCHEMBL8707686 | 0.83 | NPC1 (0.46) | NPC1RAB9ATP53MAPTSMN1; SMN2 | |
| SCHEMBL30057690 | 0.80 | MAPT (0.49) | NPC1RAB9ATP53MAPTSMN1; SMN2 | |
| SCHEMBL31068348 | 0.75 | NPC1 (0.65) | NPC1RAB9ATP53MAPTSMN1; SMN2 | |
| SCHEMBL8707789 | 0.75 | PDE4A (0.44) | MAPT | |
| SCHEMBL8708977 | 0.74 | HTR2C (0.49) | NPC1RAB9ATP53SMN1; SMN2HTR2C | |
| SCHEMBL8708166 | 0.73 | HTR2C (0.48) | NPC1RAB9AHTR2CPIK3CGMCHR1 | |
| SCHEMBL13113413 | 0.72 | PDGFRB (0.47) | NPC1RAB9ATP53MAPTHTR2C | |
| SCHEMBL19422995 | 0.72 | LMNA (0.49) | NPC1RAB9ATP53SMN1; SMN2HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998042666-A1 | NOVEL 3,4-DIALKOXYPHENYL DERIVATIVES AND THE USE THEREOF | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 1998-10-01 | — | — | WO | disclosed |