Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.39 |
| ▸ | LOX | P28300 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23586491 | 0.91 | SLC6A2 (0.46) | SLC6A2SLC6A4SLC6A3CYP2A6ALOX5 | |
| SCHEMBL21064546 | 0.85 | RAB9A (0.43) | RAB9ASLC6A2SLC6A4SLC6A3ALOX5 | |
| SCHEMBL669582 | 0.82 | RAB9A (0.45) | RAB9AALOX5CYP1A2PTGESLMNA | |
| SCHEMBL1687708 | 0.82 | ALOX5 (0.43) | RAB9ASLC6A2SLC6A4SLC6A3ALOX5 | |
| SCHEMBL21730604 | 0.78 | NR1I2 (0.37) | LTB4R | |
| SCHEMBL8233335 | 0.77 | ALOX5 (0.46) | SLC6A2SLC6A4SLC6A3CYP2A6ALOX5 | |
| SCHEMBL13187991 | 0.77 | RAB9A (0.47) | RAB9ASLC6A2SLC6A4SLC6A3CYP2A6 | |
| SCHEMBL21206330 | 0.76 | ALOX5 (0.47) | SLC6A2SLC6A4SLC6A3ALOX5CYP1A2 | |
| SCHEMBL21912351 | 0.75 | SLC6A2 (0.47) | SLC6A2SLC6A4SLC6A3CYP2A6ALOX5 | |
| SCHEMBL9826398 | 0.75 | ALOX5 (0.49) | SLC6A2SLC6A4SLC6A3CYP2A6ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998046570-A1 | SUBSTITUTED HETEROAROMATIC 5-HT1F AGONISTS | ELI LILLY AND COMPANY (US) | 1998-10-22 | — | — | WO | disclosed |