SCHEMBL8708879

SCHEMBL8708879

CCc1cc(O)nc2ccc[c]c12

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.33
GABRB2 P47870 1/20 0.33
ELANE P08246 1/20 0.33
APLNR P35414 1/20 0.32
ESR1 P03372 2/20 0.31
ESR2 Q92731 2/20 0.31
ESRRB O95718 1/20 0.31
ESRRA P11474 1/20 0.31
MAPT P10636 2/20 0.31
MEN1 O00255 1/20 0.31
GAA P10253 1/20 0.31
ALOX15 P16050 1/20 0.31
KMT2A Q03164 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
HPGD P15428 1/20 0.31
TSHR P16473 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8703598 0.78 NQO2 (0.35) MAPTMEN1GAAALOX15KMT2A
SCHEMBL2532916 0.74 TNKS2 (0.46) ELANEESR1ESR2ESRRBESRRA
SCHEMBL293534 0.71 LOXL2 (0.38)
SCHEMBL8709662 0.68 ELANE (0.44) GABRA1GABRB2ELANEGAAKMT2A
SCHEMBL8703308 0.68 ESR1 (0.40) ESR1ESR2ESRRBESRRAMEN1
SCHEMBL458549 0.66 GABRA1 (0.41) GABRA1GABRB2ELANEMAPTKDM4E
SCHEMBL27303216 0.66 ELANE (0.47) GABRA1GABRB2ELANEAPLNRMAPT
SCHEMBL13990862 0.66 RXFP1 (0.48) ESR1ESR2ESRRBESRRAMAPT
SCHEMBL1933231 0.65
SCHEMBL5510470 0.65 PDE10A (0.37) MAPTGAAKDM4EALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5770709-A BRILLIANT COLOR SHADES, GOOD FASTNESS DURING USE AT HIGH DEGREE OF FIXING DYSTAR TEXTILFARBEN GMBH & CO DEUTSCHLAND KG (DE) 1998-06-23 US disclosed