Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 6/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | DHFR | P00374 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18202481 | 0.89 | TK1 (0.52) | TK1POLB | |
| SCHEMBL8714487 | 0.89 | TK1 (0.52) | TK1POLB | |
| SCHEMBL2697383 | 0.89 | TK1 (0.47) | TK1POLBDHFR | |
| SCHEMBL8713884 | 0.89 | TK1 (0.44) | TK1POLBDHFR | |
| SCHEMBL8707772 | 0.88 | TK1 (0.51) | TK1POLB | |
| SCHEMBL8707776 | 0.87 | TK1 (0.47) | TK1POLBDHFR | |
| SCHEMBL8709836 | 0.82 | TK1 (0.58) | TK1DHFR | |
| SCHEMBL8897744 | 0.79 | TK1 (0.53) | TK1POLB | |
| SCHEMBL20061215 | 0.77 | TK1 (0.41) | TK1POLBDHFR | |
| SCHEMBL8708924 | 0.76 | TK1 (0.49) | TK1POLBDHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5837871-A | PHOSPHONATE DERIVATIVES; ANTITUMOR AGENTS, VIRICIDES | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CZ) | 1998-11-17 | — | — | US | disclosed |
| US-5726174-A | VIRICIDES, ANTITUMOR AGENTS | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CZ) | 1998-03-10 | — | — | US | disclosed |
| US-5696265-A | ANTIRETROVIRAL; ANTITUNOR AGENT | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CZ) | 1997-12-09 | — | — | US | disclosed |
| US-5693798-A | ACTIVE AGAINST RETROVIRAL DISEASES; PROPHYLAXIS | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CZ) | 1997-12-02 | — | — | US | disclosed |
| US-5688778-A | VIRICIDES | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CZ) | 1997-11-18 | — | — | US | disclosed |
| US-5686611-A | Nucleoside analogs | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CZ) | 1997-11-11 | — | — | US | disclosed |
| EP-0398231-A2 | Nucleoside analogs | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CS) | 1990-11-22 | — | — | EP | disclosed |