Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 6/20 | 0.52 |
| ▸ | NT5M | Q9NPB1 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | TYMP | P19971 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18202481 | 1.00 | TK1 (0.52) | TK1NT5MPOLBTYMP | |
| SCHEMBL8707772 | 0.99 | TK1 (0.51) | TK1NT5MPOLBTYMP | |
| SCHEMBL8707776 | 0.89 | TK1 (0.47) | TK1POLB | |
| SCHEMBL8708917 | 0.89 | TK1 (0.49) | TK1POLB | |
| SCHEMBL2697383 | 0.86 | TK1 (0.47) | TK1NT5MPOLB | |
| SCHEMBL8713884 | 0.86 | TK1 (0.44) | TK1NT5MPOLB | |
| SCHEMBL8708924 | 0.82 | TK1 (0.49) | TK1NT5MPOLBTYMP | |
| SCHEMBL8709836 | 0.82 | TK1 (0.58) | TK1 | |
| SCHEMBL16712304 | 0.81 | TYMP (0.44) | TK1NT5MTYMP | |
| SCHEMBL20061215 | 0.81 | TK1 (0.41) | TK1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5837871-A | PHOSPHONATE DERIVATIVES; ANTITUMOR AGENTS, VIRICIDES | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CZ) | 1998-11-17 | — | — | US | claimed |