⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17881257 | 1.00 | — | — | |
| SCHEMBL14382922 | 1.00 | — | — | |
| SCHEMBL7607018 | 0.85 | — | — | |
| SCHEMBL264287 | 0.85 | — | — | |
| SCHEMBL283428 | 0.85 | — | — | |
| SCHEMBL354898 | 0.85 | — | — | |
| SCHEMBL282573 | 0.85 | — | — | |
| SCHEMBL354899 | 0.85 | — | — | |
| SCHEMBL264560 | 0.85 | — | — | |
| SCHEMBL2610981 | 0.85 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11999699-B2 | Substituted pyrazole amides | Grünenthal GmbH (DE) | 2024-06-04 | — | — | US | disclosed |
| WO-2023041079-A9 | LPA INHIBITOR AND USE THEREOF | 上海金中锘美生物医药科技有限公司 | 2023-06-01 | — | — | WO | disclosed |
| US-20230025025-A1 | SUBSTITUTED PYRAZOLE AMIDES | GRUENENTHAL GMBH (DE) | 2023-01-26 | — | — | US | disclosed |
| US-7560254-B2 | Allele specific primer extension | GE HEALTHCARE BIO-SCIENCES CORP. (US) | 2009-07-14 | — | — | US | disclosed |
| US-7452698-B2 | Terminal phosphate blocked nucleoside polyphosphates | GE HEALTHCARE BIO-SCIENCES CORP. (US) | 2008-11-18 | — | — | US | disclosed |
| US-7393640-B2 | Terminal-phosphate-labeled nucleotides with new linkers | GE HEALTHCARE BIO-SCIENCES CORP. (US) | 2008-07-01 | — | — | US | disclosed |
| US-20070292879-A1 | TERMINAL PHOSPHATE BLOCKED NUCLEOSIDE POLYPHOSPHATES | GE HEALTHCARE BIO-SCIENCES CORP. (US) | 2007-12-20 | — | — | US | disclosed |
| US-7256019-B2 | Terminal phosphate blocked nucleoside polyphosphates | GE HEALTHCARE BIO-SCIENCES CORP. (US) | 2007-08-14 | — | — | US | disclosed |
| US-7244566-B2 | Detecting one or more biopolymers using terminal phosphate labeled nucleotides; labels employed are enzyme-activatable and include chemiluminescent, fluorescent, electrochemical and chromophoric moieties | GE HEALTHCARE BIO-SCIENCES CORP. (US) | 2007-07-17 | — | — | US | disclosed |
| US-7223541-B2 | Terminal-phosphate-labeled nucleotides and methods of use | GE HEALTHCARE BIO-SCIENCES CORP. (US) | 2007-05-29 | — | — | US | disclosed |
| US-20070010014-A1 | Compositions and methods for enhanced delivery to target sites | GENERAL ELECTRIC COMPANY | 2007-01-11 | — | — | US | disclosed |
| CN-1045088-C | Purine and guanine compounds as inhibitors of PNP | CHIROSCIENCE LTD (GB) | 1999-09-15 | — | — | CN | disclosed |
| US-5736549-A | INHIBITORS OF PURINE NUCLEOSIDE PHOSPHORYLASE, USED FOR TREATING OR PREVENTING TISSUE REJECTION OR SELECTIVE SUPPRESSION OF MAMMALIAN T-CELL FUNCTION | CHIROSCIENCE LIMITED (GB) | 1998-04-07 | — | — | US | disclosed |
| CN-1160402-A | Purine and guanine compounds as inhibitors of PNP | CHIROSCIENCE LTD (GB) | 1997-09-24 | — | — | CN | disclosed |
| EP-0784624-A1 | PURINE AND GUANINE COMPOUNDS AS INHIBITORS OF PNP | Chiroscience Limited (GB) | 1997-07-23 | — | — | EP | disclosed |
| WO-1996011200-A1 | PURINE AND GUANINE COMPOUNDS AS INHIBITORS OF PNP | CHIROSCIENCE LIMITED (GB) | 1996-04-18 | — | — | WO | disclosed |
| US-4525203-A | ((3,4,5,6-Tetrahydro-2H-pyran-2-yl)methoxy)oxabicycloalkane herbicides | SHELL OIL COMPANY (US) | 1985-06-25 | — | — | US | disclosed |