Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.37 |
| ▸ | TPMT | P51580 | 3/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | KDM6B | O15054 | 1/20 | 0.31 |
| ▸ | TET3 | O43151 | 1/20 | 0.31 |
| ▸ | KDM4A | O75164 | 1/20 | 0.31 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KDM5A | P29375 | 1/20 | 0.31 |
| ▸ | KDM5C | P41229 | 1/20 | 0.31 |
| ▸ | ASPH | Q12797 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8632322 | 0.89 | NR4A2 (0.43) | NR4A2TPMTHCAR2L3MBTL1TSHR | |
| SCHEMBL940913 | 0.85 | — | — | |
| SCHEMBL8709279 | 0.85 | — | — | |
| SCHEMBL8627462 | 0.67 | CA12 (0.50) | TSHRHPGDKDM4EALDH1A1MAPT | |
| SCHEMBL4729951 | 0.65 | — | — | |
| SCHEMBL7956876 | 0.64 | NR4A2 (0.42) | NR4A2TPMTHCAR2L3MBTL1TTR | |
| Hydrochloric Acid SCHEMBL11786036 | 0.63 | L3MBTL1 (0.60) | NR4A2TPMTHCAR2L3MBTL1TSHR | |
| SCHEMBL5151230 | 0.62 | — | — | |
| SCHEMBL19992920 | 0.62 | — | — | |
| SCHEMBL69933 | 0.62 | NR4A2 (0.43) | NR4A2TPMTHCAR2L3MBTL1TTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998042347-A1 | PHARMACEUTICAL COMPOSITION CONTAINING A PHOSPHORYLAMIDE AND AN AYNTIBIOTIC | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-10-01 | — | — | WO | disclosed |