Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8587349 | 0.72 | POLB (0.39) | KDM4EMAPTMMP3KMT2AMEN1 | |
| SCHEMBL8629804 | 0.71 | KDM4E (0.56) | KDM4EMAPTRAB9AKMT2AMEN1 | |
| SCHEMBL7376159 | 0.70 | KMT2A (0.59) | KDM4EMAPTRAB9AKMT2AMEN1 | |
| SCHEMBL9590560 | 0.70 | KMT2A (0.39) | KDM4EMAPTTP53MMP3KMT2A | |
| SCHEMBL8626710 | 0.69 | KLK7 (0.58) | KDM4ERAB9ANPC1HPGDALDH1A1 | |
| SCHEMBL8630316 | 0.69 | MAPT (0.41) | KDM4EMAPTTP53RAB9ANPC1 | |
| SCHEMBL11427056 | 0.68 | TAS1R3 (0.46) | KDM4EKMT2AMEN1L3MBTL1HPGD | |
| SCHEMBL12195572 | 0.68 | TP53 (0.47) | KDM4EMAPTTP53MMP3RAB9A | |
| SCHEMBL8586691 | 0.68 | RAB9A (0.48) | KDM4EMAPTTP53RAB9AS1PR4 | |
| SCHEMBL3062337 | 0.66 | GAA (0.39) | KDM4EMAPTKMT2AMEN1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998042347-A1 | PHARMACEUTICAL COMPOSITION CONTAINING A PHOSPHORYLAMIDE AND AN AYNTIBIOTIC | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-10-01 | — | — | WO | disclosed |