Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.34 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.34 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 3/20 | 0.33 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.33 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19223206 | 0.71 | UHRF1 (0.46) | KDRSMARCA2SMARCA4SORT1UHRF1 | |
| SCHEMBL8716665 | 0.71 | UHRF1 (0.42) | KDRSMARCA2SMARCA4SORT1JAK2 | |
| SCHEMBL14197584 | 0.66 | TLR8 (0.46) | SMARCA2SMARCA4UHRF1 | |
| SCHEMBL8713505 | 0.65 | KDM4E (0.43) | — | |
| SCHEMBL18386505 | 0.64 | ABL1 (0.49) | — | |
| SCHEMBL11468465 | 0.64 | ABL1 (0.49) | — | |
| SCHEMBL27634055 | 0.63 | SMARCA2 (0.47) | KDRSMARCA2SMARCA4SORT1UHRF1 | |
| SCHEMBL487318 | 0.63 | UHRF1 (0.48) | KDRUHRF1 | |
| SCHEMBL26706918 | 0.62 | NOS2 (0.57) | — | |
| SCHEMBL883728 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0840609-A1 | USE OF UNSUBSTITUTED AND SUBSTITUTED N-(PYRROL-1-YL)PYRIDINAMINES AS ANTICONVULSANT AGENTS | HOECHST MARION ROUSSEL, INC. (US) | 1998-05-13 | — | — | EP | claimed |
| WO-1997004777-A1 | USE OFF UNSUBSTITUTED AND SUBSTITUTED N-(PYRROL-1-YL)PYRIDINAMINES AS ANTICONVULSANT AGENTS | HOECHST MARION ROUSSEL, INC. (US) | 1997-02-13 | — | — | WO | claimed |